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New England Patriots vs Buffalo Bills Picks and Predictions NFL Week 13 Monday Night Football

New England Patriots vs Buffalo Bills picks, predictions, and game preview for this Week 13 Monday Night Football Game.

New England Patriots vs. Buffalo Bills odds

This Monday Night Football game is set to kickoff on December 6, 2021 at 8:15pm et at Highmark Stadium in Orchard Park.

The latest NFL odds have the Buffalo Bills listed as a -3 point favorite against the spread with the over/under at 41 total points.

56% of the NFL betting public have their money behind the New England Patriots as the road underdog.

These teams faced each other twice last season and Buffalo was able to get both wins by scoring a combined 72 points while giving up only 30 combined points.

In those two matchups, Cam Newton was the starting quarterback, but now with Mac Jones you probably won’t witness these two upcoming December games against the Bills with 30 combined points.

New England Patriots Betting Preview

Speaking of Mac Jones, he’s now led this New England Patriots team to an 8-4 record and a perfect 5-0 on the road this season.

They currently sit at the top of the AFC East after winning their last six games in a row including the blow out win 36-13 last Sunday against the Titans.

In that last game, the Patriots defense held the Titans to just 85 total passing yards, but they gave up 270 total rushing yards. Mac Jones threw for a career-high 310 yards and two touchdowns.

The bad news for New England is that they downgraded linebacker Ronnie Perkins to out for this game and kicker Nick Folk is currently listed as questionable.

The Patriots on the road this season have the best defense in the league that’s only giving up an average of 11.6 points per game while their offense is scoring an average of 25.2 points per game.

New England is 6-0 against the spread in their last 6 games and the total has gone over in 6 of the Patriots last 8 games.

Buffalo Bills Betting Preview

On the other side of the field, the Buffalo Bills who everyone talking about in the beginning of the season, but now they’ve been kind of got forgotten about while they watched New England win six in a row.

This matchup is the perfect opportunity for the Bills to make a statement to show everyone they’re still hungry to win the AFC East and eventually try to represent the AFC in the Super Bowl.

They crushed the banged up New Orleans Saints on Thanksgiving 31-6, but they’ll need to play even better than they did if that want to get that statement win against the Patriots.

Dane Jackson will replace star cornerback Tre’Davious White who unfortunately tore his ACL last game against the Saints. The Bills at home this season have the 6th best offense and the 7th best defense in the league.

They are scoring an average of 28 points per game while on defense giving up an average of only 19.2 points per game.

Buffalo is 10-2 straight up in their last 12 games at home and the total has gone over in 4 of the Bills last 6 games against an opponent in the AFC.

Free NFL Picks:

For this New England Patriots vs Buffalo Bills Monday Night Football game, we’re taking the Bills Team Total to go over the 21.5 points and laying the -108 price. Then if you want free access to our First Half Pick going in this game, then click here. Our first half football picks went a red hot 4-0 this weekend and we’re ready to continue that streak, so if you want to receive the strong info we have going behind this Patriots vs Bills First Half pick then just click here. Let’s sweep this Monday Night football board together.

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